AN UNBIASED VIEW OF FRACTAL STORM (SELF-LAID

Within the LSD-sure crystal construction, the facet chain of the lid residue L209EL2 varieties intensive hydrophobic contacts with each LSD and encompassing residues in TMs III, IV, and V (Figure 4C). Once the lid moved aside to show the binding pocket in simulation, many of such contacts broke. We Hence hypothesized that L209EL2 functions like a l